Prof. Marianne Chapman

BMBS, PhD, FFARCSI, FANZCA, FCICM

Professor Chapman is an academic in the School of Medicine in the University of Adelaide and a clinician in the Intensive Care Unit at the Royal Adelaide Hospital, with a PhD in the area of gastrointestinal pathophysiology and nutrition in the critically ill. She is a Fellow of the Australian & New Zealand College of Anaesthetists, the Australian College of Intensive Care Medicine and the Faculty of Anaesthetists in the Royal College of Surgeons in Ireland. She is a Professor in the School of Medicine at the University of Adelaide and an Adjunct Professor in the Department of Epidemiology & Preventive Medicine at Monash University in Melbourne. She has been the Director of Research in the ICU at the Royal Adelaide Hospital since 1998. As Director of Research she leads a group of researchers (medical, nursing, allied health and scientists) focused on clinical research in the critically ill which covers a breadth of areas. The significant successes of the broader group in terms of grant funding, publication and awards reflect her ability to provide support and foster enthusiasm and success in her colleagues and trainees. Her particular area of interest relates to gastrointestinal pathophysiology, nutrition and metabolism but also extends to other areas such as thyroid function in sepsis etc. She has previously held roles on the Board of Examiners for the College of Intensive Care Medicine, the Abstract Review Committee for the Australian & New Zealand Intensive Care Society and the Scientific Committee for the Intensive Care Foundation.

Professor Chapman is a recognised world leader in the area of gastrointestinal pathophysiology in critical illness and has received national and international recognition, with invitations for the presentation of her work at many national and international meetings. In the past 5 years, Professor Chapman has received more than $8 million in research grant funding (including as CI/AI on NHMRC/ARC project and CRE grants). She was CIA on the largest NHMRC funded grant in the field of critical care nutrition (APP1078026) the TARGET trial published in the NEJM in 2018.

Professor Chapman is also a member of the Adelaide based NHMRC funded Centre of Research Excellence (CRE) in Nutrition. This group is highly productive and successful both in terms of publication output and accessing grant funding. A major strength of the group is in the cross-fertilisation across specialty areas such that ideas and techniques utilised in researching nutrition for example in the aged or in diabetics can also be used in critical illness providing novel insights. She also has extensive interstate collaborations (e.g. Professor Andrew Davies) and has been participating investigator in ~20 multi-centre studies (mostly clinical trials performed with the Australian & New Zealand Intensive Care Society - Clinical Trials Group – see rgms CV-Pub). She continues to collaborate with other international leaders in critical care nutrition such as Professor Daren Heyland (Canada).

Professor Chapman and Associate Professor Deane have a number of commercial collaborations with Theravance-USA, GSK-USA and TAKEDA completing single-centre, phase II, investigator-driven pharmaceutical-sponsored trials on the safety and efficacy of new pre-motility drugs. She has had involvement in the development and testing of a novel device for the insertion of small intestinal feeding catheters (see rgms CV-Pub).

Professor Chapman is registered as a Principal Supervisor for higher degree students at the University of Adelaide. She has had 6 completions to date. Professor Chapman is also a supervisor and assessor of medical students completing Honours degrees and an undergraduate examiner for MBBS at the University of Adelaide. She also reviews for multiple journals, including Anaesthesia and Intensive Care, Intensive Care Medicine, Critical Care Medicine, Critical Care & Resuscitation and Clinical Nutrition. She is also an external assessor of grant applications for the NHMRC, Intensive Care Foundation, the Revised Thuthuka Programme in South Africa and the Australian and New Zealand College of Anaesthesia, National Research Foundation.

She has published just over 160 peer-reviewed papers (over 54 in the past 5 years, 3 invited book chapters, 5 invited reviews and 1 invited editorial). A number of these publications have appeared in the highest ranking journals in her area of critical care, including in ‘Critical Care Medicine’, ‘Intensive Care Medicine’ and ‘Critical Care’. Professor Chapman has also had many publications in high-ranking journals outside of her field, including ‘Gut’, the ‘American Journal of Clinical Nutrition’, the ‘Journal of Clinical Endocrinology and Metabolism’, ‘Diabetes Care’ and ‘Diabetes’. She has had 33 publications with over 50 citations.

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